FILE - This Thursday, March 18, 2021 file photo shows syringes filled with the Moderna COVID-19 vaccine at a pop up site in the Queens borough of New York. According to results released on Monday, March 29, 2021, The U.S government’s first look at the real-world use of COVID-19 vaccines found their effectiveness was nearly as robust as it was in controlled studies. (AP Photo/Mary Altaffer)

FILE - This Thursday, March 18, 2021 file photo shows syringes filled with the Moderna COVID-19 vaccine at a pop up site in the Queens borough of New York. According to results released on Monday, March 29, 2021, The U.S government’s first look at the real-world use of COVID-19 vaccines found their effectiveness was nearly as robust as it was in controlled studies. (AP Photo/Mary Altaffer)

COVID vaccine found highly effective in real-world U.S. study

The two vaccines available since December — Pfizer and Moderna — were highly effective at 90% after two doses,

The U.S. government’s first look at the real-world use of COVID-19 vaccines found their effectiveness was nearly as robust as it was in controlled studies.

The two vaccines available since December — Pfizer and Moderna — were highly effective at 90% after two doses, the Centers for Disease Control and Prevention reported Monday. In testing, the vaccines were about 95% effective in preventing COVID-19.

“This is very reassuring news,” said the CDC’s Mark Thompson, the study’s lead author. “We have a vaccine that’s working very well.”

The study is the government’s first assessment of how the shots have been working beyond the drugmakers’ initial experiments. Results can sometimes change when vaccines are used in larger, more diverse populations outside studies.

With nearly 4,000 participants from six states, the study focused on health care workers, first responders and other front-line workers who had first priority for the shots because they are at higher risk. They were given nasal swab test kits to use every week to check for signs of a coronavirus infection.

“The evidence base for (currently available) COVID-19 vaccines is already strong, and continues to mount ever higher with studies like this one,” said David Holtgrave, dean of the University at Albany’s School of Public Health, in an email.

The study included roughly 2,500 volunteers who had completed two vaccine doses, about 500 who got one dose and about 1,000 who did not get vaccinated between mid-December and mid-March.

The researchers counted 205 infections, with 161 of them in the unvaccinated group. Of the remaining 44, the CDC said 33 of them were in people apparently infected within two weeks of a shot. Experts say it takes two weeks before a dose takes full effect.

No one died, and only two were hospitalized. Thompson did not say whether the people hospitalized were vaccinated or not.

Besides the 90% figure for two doses, the study found it was 80% effective for participants two weeks or more after a first dose.

CDC Director Dr. Rochelle Walensky called the study’s findings “tremendously encouraging.”

“Our national vaccination efforts are working,” she said during a White House press briefing Monday. She added that over 93 million Americans have received at least one vaccine dose and over 51 million people have been fully vaccinated.

Different researchers have tried to look at how the vaccines have performed in real-life conditions, including work done in Israel and the United Kingdom, and a U.S. study of Mayo Clinic patients.

Unlike the Mayo study, which focused on hospitalization and death, the CDC study looked for any infection — including infections that never resulted in symptoms, or were detected before people started feeling sick.

About two-thirds of the vaccinations in the study were Pfizer shots, one-third were Moderna and five people got the newest single-dose shot from Johnson & Johnson. The study was done in Miami; Duluth, Minnesota; Portland, Oregon; Temple, Texas; Salt Lake City; and Phoenix and other areas in Arizona.

Moderna, meanwhile, announced Monday that it had shipped its 100 millionth dose to the U.S. government, meeting its pledge to supply that amount by the end of March. The company said it expects to meet its next deadlines, of delivering another 100 million doses by the end of May and its final 100 million by the end of July.

READ MORE: B.C.’s frontline worker vaccine program in flux as AstraZeneca use paused for under-55s

___

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.

Mike Stobbe, The Associated Press


Like us on Facebook and follow us on Twitter.

Want to support local journalism during the pandemic? Make a donation here.

Coronavirusvaccines

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

Vancouver Police Department. (Black Press Media files)
Abbotsford man named as victim of fatal weekend shooting in Vancouver

Harpreet Dhaliwal, 31, killed outside of Cardero’s restaurant in Coal Harbour

Joudelie King wants to get out and live life to the fullest, but there are places she can’t go because they don’t meet her accessibility needs. (submitted photo)
New online tool provides accessibility map for people with disabilities

The myCommunity BC map provides accessibility info for nearly 1,000 locations in the province

B.C. Agriculture in the Classroom is offering free school tours of The Pencil Patch learning garden in Abbotsford in April, May and June.
Agriculture in the Classroom offers free school tours at learning garden

The Pencil Patch in Abbotsford provides 15 outdoor learning stations

Alisa Gusakova was one of two Grade 12 Chilliwack students who received a $5,000 Horatio Alger Canadian Scholarship earlier this year. Now, a fundraiser has been created for the teen after her mother was killed. (Jenna Hauck/ Chilliwack Progress file)
Fundraiser launched for daughter of Chilliwack woman killed

Money raised will help Chilliwack teen attend UFV to earn business degree

Chilliwack Search and Rescue volunteers say that a call on April 17 on Vedder Mountain was affected by bikers who rode through the rescue site, throwing rocks onto members and the patient. (Chilliwack Search and Rescue image)
Chilliwack Search and Rescue team, and patient, sprayed with rocks and dirt during rescue

Volunteer crew speaks out after riders on Vedder Mountain show no courtesy at accident scene

In this image from NASA, NASA’s experimental Mars helicopter Ingenuity lands on the surface of Mars Monday, April 19, 2021. The little 4-pound helicopter rose from the dusty red surface into the thin Martian air Monday, achieving the first powered, controlled flight on another planet. (NASA via AP)
VIDEO: NASA’s Mars helicopter takes flight, 1st for another planet

The $85 million helicopter demo was considered high risk, yet high reward

Carver Ken Sheen had almost finished work on a large cowboy carving commissioned by the City of Williams Lake to replace the original overlooking the Stampede Grounds when fire broke out Friday, April 18 at his property between Williams Lake and Quesnel. (Pine River Carving Facebook photos)
Cow boss statue destined for Williams Lake Stampede Grounds goes up in flames

Carver Ken Sheen lost the statue, all his tools and his shop in the blaze

B.C. Labour Minister Harry Bains. (Hansard TV)
B.C. moves to protect employee pay for COVID-19 vaccination

Most won’t need to take time off work, labour minister says

New figures show Canadian housing prices outpacing those in other developed countries. (Black Press Media file photo)
Canadian housing prices fastest rising in the world

Relative to 2000, housing prices have risen by a factor of more than 2.5

Russ Ball (left) and some of the team show off the specimen after they were able to remove it Friday. Photo supplied
80-million-year-old turtle find on B.C. river exciting fossil hunters

Remains of two-foot creature of undetermined species will now make its home at the Royal BC Museum

Large gatherings of people at Kitsilano Beach on Saturday, April 17, 2021. (Walter Wells/Twitter)
Vancouver police to reassess enforcement of COVID rules at outdoor parties: mayor

No tickets were given out for a large outdoor party at Kitsilano Beach

British Columbia’s provincial flag flies in Ottawa, Friday July 3, 2020. THE CANADIAN PRESS/Adrian Wyld
Wildfire fanned by winds near Merritt prompts evacuation alert

BC Wildfire Service says the suspected human-caused blaze was fanned by winds

The Rogers logo is photographed in Toronto on Monday, September 30, 2019. THE CANADIAN PRESS/Tijana Martin
Rogers investigating after wireless customers complain of widespread outage

According to Down Detector, problems are being reported in most major Canadian cities

Most Read